What is indomethacin?

What is indomethacin used for?

Indomethacin is used to relieve moderate to severe pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints), rheumatoid arthritis (arthritis caused by swelling of the lining of the joints), and ankylosing spondylitis (arthritis that mainly affects

Is indomethacin a pain killer?

Indomethacin is used to relieve pain, swelling, and joint stiffness caused by arthritis, gout, bursitis, and tendonitis. It is also used to relieve pain from various other conditions. This medication is known as a nonsteroidal anti-inflammatory drug (NSAID).

Is indomethacin stronger than ibuprofen?

Indomethacin is a much stronger anti-inflammatory medication than ibuprofen. So, 50 mg. of indomethacin is much stronger than 600 mg.

What is indomethacin and what are the side effects?

Common side effects of Indocin (indomethacin) and Indocin IV (indomethacin) for Injection include:

  • vomiting,
  • upset stomach,
  • heartburn,
  • diarrhea,
  • a feeling of bowel fullness,
  • constipation,
  • bloating,
  • gas,

Who should not take indomethacin?

stomach or intestinal ulcer. ulcerative colitis, an inflammatory condition of the intestines. liver problems. bleeding of the stomach or intestines.

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How long is it safe to take indomethacin?

Adults—75 to 150 milligrams (mg) per day, divided into three or four equal doses, and taken for 1 to 2 weeks as determined by your doctor. Children 15 years of age and older—Dose is based on body weight and must be determined by your doctor.

What painkiller can I take with indomethacin?

by Drugs.com

Yes, you can take Tylenol while taking indomethacin. As long as you do not exceed the recommended daily doses you can safely alternate the medicines, or take together for added pain relief. The usual dose of indomethacin for pain in adults is 20mg 3 times a day or 40mg 2 to three times a day.

What can I take instead of indomethacin?


  • Indocin (indomethacin) Prescription only.
  • 8 alternatives.
  • aspirin (aspirin) Prescription or OTC.
  • Celebrex (celecoxib) Prescription only.
  • Voltaren (diclofenac) Prescription only.
  • Lodine (etodolac) 30% of people say it’s worth it.
  • meloxicam (meloxicam) Prescription only.
  • naproxen (naproxen) Prescription or OTC.

Is indomethacin good for back pain?

A short-term double-blind sequential trial of indomethacin against placebo in the treatment of low back pain, with and without nerve root pain such as sciatica, showed that indomethacin was significantly more effective than placebo in the group with nerve root pain.

Does indomethacin make you sleepy?

This medicine may cause some people to become dizzy, lightheaded, drowsy, or less alert than they are normally. Even if taken at bedtime, it may cause some people to feel drowsy or less alert on arising.

Which is stronger naproxen or indomethacin?

Aleve (naproxen) works well for treating mild to moderate pain or inflammation, and lasts longer than other NSAIDs. In studies, Indocin (indomethacin) was more effective than Tylenol for treating osteoarthritis pain.

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How long does Indomethacin 50 mg stay in your system?

The mean half- life of indomethacin is estimated to be about 4.5 hours. With a typical therapeutic regimen of 25 or 50 mg t.i.d., the steady-state plasma concentrations of indomethacin are an average 1.4 times those following the first dose.

How bad is indomethacin?

Heart risk. Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID). NSAIDs may increase your risk of heart attack, heart failure, or stroke. This risk may be higher if you’re taking it long term, at high doses, or if you already have heart problems or risk factors for heart disease, such as high blood pressure.

Does indomethacin lower your immune system?

These results indicate that indomethacin affects selective components of the immune and hemopoietic cells at dose levels that cause no other significant pathological alterations.

Is it OK to take ibuprofen with indomethacin?

Using ibuprofen together with indomethacin is generally not recommended. Combining these medications may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

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